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Oxyma

The perfect activator for peptide synthesis at elevated temperature.

 

Overview

Oxyma Pure used with DIC produces peptides with increased yield and decreased epimerization when used as an alternative to HOBt1 . This safe, non-explosive auxiliary nucleophile works with carbodiimide coupling strategies to provide the best results for a peptide synthesis. Additionally, the use of DIC/Oxyma avoids side reactions associated with high levels of base (≥ 1 equiv. DIEA) using onium salt methods such as HBTU/DIEA.

1R. Subirós-Funosas, et al. (2009) Chem. Eur. J., 15, 9394.

Features

  • Extremely fast acylation rates
  • Non-explosive (compared to HOBt)
  • Low cost
  • Highly soluble in peptide synthesis solvents


Products

#S001-C
100g
$70
#S001-D
1kg
$295

Questions?


We’re happy to help.

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