Welcome to CEM.com

Gas Addition Accessory

GAS ADDITION FOR MICROWAVE SYNTHESIS - HYDROGENATIONS, CARBONYLATIONS

Discover Gas Addition



BENEFIT FROM MICROWAVE ENERGY FOR REACTIONS USING GASEOUS REAGENTS

SYSTEM FEATURES:

  • Applicable to a wide range of chemistries
  • Hydrogenations, Carbonylations (Hydroformylations), Carbon-Carbon couplings, Reductive Aminations
  • Hydrogenations complete in less than 10 min!
  • Complete control of gas addition, vacuum purging, and venting
  • Operating limits up to 250°C and 250 PSI (17 bar)
  • Working volume up to 50mL
  • 10mL vessel: 2-7mL working volume
  • 80mL vessel: 15-50mL working volume
  • Works with any gas source (tank, houseline or other)
  • Incorporates in-situ fiber optic temperature control
  • Upgrade any existing Discover microwave synthesizer
 
Experience the benefits of using microwave energy for reactions that require gaseous reagents. The Gas Addition accessory for the Discover line of microwave synthesizers allows the addition of non-corrosive gaseous reagents to reaction mixtures for a variety of applications including hydrogenations, carbonylations (hydroformylations), carbon-carbon couplings, reductive aminations, and more.


The Gas Addition Accessory (Patented: US 7,955,479; EP1996539) offers significant improvement over standard hydrogenation techniques. Conventional hydrogenation techniques typically use a gas balloon connected to a reaction vessel syringe. The Gas Addition Accessory for the Discover microwave synthesizer allows for safe heating under higher gas pressure conditions which is beneficial for driving these reactions to completion. The use of a balloon is avoided and standard remote gas sources (tank, houseline) can be used which improves overall safety. Additionally, the microwave system is completely isolated from the source during the reaction. Monitoring of the pressure and temperature is performed at all times as the reaction takes place. Simply watch your gas consumption and re-charge as necessary.

CARBONYLATIONS (HYDROFORMYLATION):

CARBONYLATIONS (HYDROFORMYLATION)
Microwave-Assisted Carbonylation and Cyclocarbonylation of Aryl Iodides under Ligand Free Heterogeneous Catalysis
J. Org. Chem., 75, 1841-1847 2010
DOI: 10.1021/jo9021315

Microwave-Assisted Domino Hydroformylation/Cyclization Reactions: Scope and Limitations
Synthesis 17, 2901-2914 2010
DOI: 10.1055/s-0030-1258207

Microwaves Make Hydroformylation a Rapid and Easy Process
Org. Lett. 8, 3725-3727 2006
DOI: 10.1021/ol061312v

HYDROGENATIONS:

HYDROGENATIONS
Rhodium-Catalyzed Enantioselective Hydrogenation of (E)-Enol Acetate Acids
Advanced Synthesis & Catalysis 355, 1449-1454 2013
DOI: 10.1002/adsc.201200934

Microwave-Assisted Cross-Coupling and Hydrogenation Chemistry by Using Heterogeneous Transition-Metal Catalysts: An Evaluation of the Role of Selective Catalyst Heating
Chem. Eur. J. 15, 11608-11618 2009
DOI: 10.1002/chem.200902044

Microwave-Assisted Hydrogenation of Pyridines
Synlett, 8 1125-1128 2008
DOI: 10.1055/s-2008-1072717

Simple and Efficient Microwave-Assisted Hydrogenation Reactions at Moderate Temperature and Pressure
Synlett, 1, 131-135 2007
DOI: 10.1055/s-2006-958428

CARBON-CARBON COUPLING:

Preparation of Nonsymmetrically Substituted Stilbenes in a One-Pot Two-Step Heck Strategy Using Ethene as a Reagent
J. Org. Chem., 73, 3854-3858 2008
DOI: 10.1021/jo800235c

Set Descending Direction

2 Item(s)

  1. 908255

    10 mL Gas Addition Kit for Discover SP and Discover S-Class Systems

    Part #: 908255

    Discover accessory for hydrogenation, carbonylation, or formylation reactions. Learn More
  2. 80 mL Gas Addition Kit for Discover SP and Discover S-Class Systems

    80 mL Gas Addition Kit for Discover SP and Discover S-Class Systems

    Part #: 925530

    Discover accessory for hydrogenation, carbonylation, or formylation reactions. Learn More

Set Descending Direction

2 Item(s)

English |  Français |  Deutsch |  Italiano |  日本語 |  Español