We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Microwave Peptide Synthesizer
Liberty Blue 2.0
Microwave Peptide Synthesizer
Liberty Blue 2.0
Overview
The Liberty Blue™ 2.0 is the exciting next generation of the best-selling peptide synthesizer in the world. Compared to its predecessor, the Liberty Blue 2.0 features the ability to make cleaner and longer peptides with a new level of robustness. The system features a 4-minute cycle time along with a 90% solvent reduction based on High Efficiency Solid Phase Peptide synthesis (HE-SPPS). The Liberty Blue 2.0 features the latest in engineering for fluidic deliveries, true internal temperature feedback control, and software control with 21 CFR Part 11 compliance.Features
- 4 min cycle time
- 90% waste reduction (HE-SPPS)
- Flex-Add™ critical reagent delivery system (patented)
- True Internal fiber-optic temperature control
- 0.005 - 5 mmol scale range
- 27 amino acid positions
- Integrated RV Camera
- High-throughput upgrade options (HT4, HT12)
Unmatched Quality
A new level of peptide purity.
The Liberty Blue 2.0 provides the ability to make even higher purity peptides than previously possible with the original Liberty Blue system. This is based on advances in the system fluidics, reaction vessel environment, and chemistry methodology.
- Optimized microwave chemistry methodology with ProTide resins
- Cleanest reaction environment with updated headspace flushing technology
- More direct optimized flow paths
- Digitally variable N2 control for optimized bubbling, purging, and draining
View application data
 |
BarstarLength: 89 amino acidsSynthesis Time: 14 hr 43 min. Waste Generated: 2696 mL Scale: 0.05 mmol View chromatogram |
FlexAdd
The best way to deliver critical reagents.
- Infinitely variable – deliver whatever volume you want (unlike sample loops)
- No priming ever
- No washing and less complex than syringe pumps
High Throughput (HT) Loaders
High-throughput peptide synthesis made easy.
- Automated synthesis of 4 peptides (individual 20mer’s completed every 4 hours)
- The Liberty Blue 2.0 paired with the HT4 allows for automated synthesis of 4 peptides
- Individual 20mer's completed every 4 hours
Software
Flexible, Powerful Software
Easy and Flexible Sequence Programming
The method editor on the Liberty Blue allows full customization of reaction parameters.
Program Post-Synthesis Modification
Versatile options enabling orthogonal deprotection for modifications like branching and cyclization.
Full Suite of Calculator Tools
Convenient calculators provide the reagents and amounts for a run.
Pause, Edit, Monitor at any Step
Easily pause, edit, and monitor reactions from the run screen.
Applications
Synthesize standard and complex peptides.
The Liberty 2.0 series, like preceding models, utilizes CEM’s High-Efficiency Solid Phase Peptide Synthesis (HE-SPPS) and CarboMAX coupling methodologies,| Branched Peptides | High Throughput Synthesis |
| Cyclized Peptides | N-Methyl Peptides |
| Disulfide Bonding | Peptoids |
| Glycopeptides (N/O-linked) | Phosphopeptides |
