OxymaPure

OxymaPure

OxymaPure® used with DIC produces peptides with increased yield and decreased epimerization when used as an alternative to HOBt.¹ This safe, non-explosive auxiliary nucleophile works with carbodiimide coupling strategies to provide the best results for a peptide synthesis. Additionally, the use of DIC/Oxyma avoids side reactions associated with high levels of base (≥ 1 equiv. DIEA) using onium salt methods such as HBTU/DIEA.

Standard Specifications

• Extremely fast acylation rates
• Non-explosive (compared to HOBt)
• Low cost
• Highly soluble in peptide synthesis solvents