Microwave Peptide Synthesizer
Liberty 2.0

A powerful entry-level peptide synthesizer.

 

Overview


The entry-level system for CEM’s best in class microwave peptide synthesizer line. The Liberty 2.0 provides advantages over existing peptide synthesizers with it’s patented use of microwave irradiation during both the deprotection and coupling steps (12 minute cycle times), in-situ temperature control, Flex-Add™ delivery system, and efficient solvent usage.



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Unique Chemistry

  • Microwave deprotection and coupling (patented)
  • CarboMAX™ coupling chemistry (patented)

Features

  • 12 min Cycle Time
  • Flex-Add™ critical reagent delivery system (patented)
  • True Internal fiber-optic temperature control
  • 0.005 - 5 mmol scale range
  • 27 amino acid positions

CarboMAX

CarboMAX

The best coupling method for peptide synthesis.

  • The fastest and most complete coupling
  • Stabilizes acid sensitive linkages which are problematic for standard carbodiimide chemistry (phospho, glyco, hyper-acid linkages)
  • Unmatched low-level of epimerization for all 20 amino acids due to faster activation (faster o-acylisourea formation)

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CarboMAX

FlexAdd

The best way to deliver critical reagents.

  • Infinitely variable – deliver whatever volume you want (unlike sample loops)
  • No priming ever
  • No washing and less complex than syringe pumps


High Throughput (HT) Loaders

High Throughput (HT) Loaders

High-throughput peptide synthesis made easy.

  • Automated synthesis of 4 peptides (individual 20mer’s completed every 4 hours)
  • The Liberty 2.0 paired with the HT4 allows for automated synthesis of 4 peptides
  • Individual 20mer's completed every 4 hours

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Software

Flexible, Powerful Software

The newly updated software is both flexible and easy to use, making sure nothing stands between you and your synthesis. Customize methods with unique monomers, orthogonal deprotection, branching, cyclizing, and more. Easily check on reactions on the run screen, where the run can be edited, paused, and resumed at any time.



Method Editor

Easy and Flexible Sequence Programming

The method editor on the Liberty Blue allows full customization of reaction parameters.

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Alternate Chemistry and Post-Synthetic Modification

Program Post-Synthesis Modification

Versatile options enabling orthogonal deprotection for modifications like branching and cyclization.

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Calculator for Reagents

Full Suite of Calculator Tools

Convenient calculators provide the reagents and amounts for a run.

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Edit on the Run

Pause, Edit, Monitor at any Step

Easily pause, edit, and monitor reactions from the run screen.

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Applications

Synthesize standard and complex peptides.

The Liberty 2.0 series, like preceding models, utilizes CEM’s High-Efficiency Solid Phase Peptide Synthesis (HE-SPPS) and CarboMAX coupling methodologies.

Branched Peptides
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Cyclized Peptides
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Disulfide Bonding
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Glycopeptides (N/O-linked)
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High Throughput Synthesis
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N-Methyl Peptides
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Peptoids
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Phosphopeptides
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Accessories and Related Products



HT 4

HT4

The HT4 automates peptide synthesis with the ability to queue up to 4 peptides. New reactions can be programmed at any time, even while another sample is running.

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Razor

Razor

The Razor from CEM provides high temperature, rapid cleavage on up to 12 samples simultaneously. Finish cleavage in just 30 minutes with the Razor.

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Prodigy

Prodigy

The Prodigy Preperative HPLC is a purification system optimized for use with biomolecules like peptides and proteins. The fully integrated temperature control for the column and mobile phase is a powerful tool, especially for difficult or hydrophobic samples

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