Microwave Peptide Synthesizer
Liberty Blue 2.0
Overview
The Liberty Blue™ 2.0 is the exciting next generation of the best-selling peptide synthesizer in the world. Compared to its predecessor, the Liberty Blue 2.0 features the ability to make cleaner and longer peptides with a new level of robustness. The system features a 4-minute cycle time along with a 90% solvent reduction based on High Efficiency Solid Phase Peptide synthesis (HE-SPPS). The Liberty Blue 2.0 features the latest in engineering for fluidic deliveries, true internal temperature feedback control, and software control with 21 CFR Part 11 compliance
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Unique Chemistry
- CarboMAX™ coupling chemistry (patented)
- Microwave deprotection and coupling (patented)
- Nitrogen Headspace Flushing (patent pending)
Features
- 4 min cycle time
- 90% waste reduction (HE-SPPS)
- Flex-Add™ critical reagent delivery system (patented)
- True Internal fiber-optic temperature control
- 0.005 - 5 mmol scale range
- 27 amino acid positions
- Integrated RV Camera
- High-throughput upgrade options (HT4, HT12)
Unmatched Quality
A new level of peptide purity.
The Liberty Blue 2.0 provides the ability to make even higher purity peptides than previously possible with the original Liberty Blue system. This is based on advances in the system fluidics, reaction vessel environment, and chemistry methodology.
- Optimized microwave chemistry methodology with ProTide resins
- Cleanest reaction environment with updated headspace flushing technology
- More direct optimized flow paths
- Digitally variable N2 control for optimized bubbling, purging, and draining
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BarstarLength: 89 amino acidsSynthesis Time: 14 hr 43 min. Waste Generated: 2696 mL Scale: 0.05 mmol View Chromatogram |
High Throughput (HT) Loaders
High-throughput peptide synthesis made easy.
- Automated synthesize of 4 or 12 peptides (individual 20mer’s completed every 1.5 hours)
- The Liberty Blue 2.0 paired with either the HT4 or the HT12 keeps up with conventional parallel systems
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Software
Flexible, Powerful Software
The newly updated software is both flexible and easy to use, making sure nothing stands between you and your synthesis. Customize methods with unique monomers, orthogonal deprotection, branching, cyclizing, and more. Easily check on reactions on the run screen, where the run can be edited, paused, and resumed at any time.
Easy and Flexible Sequence Programming
The method editor on the Liberty Blue allows full customization of reaction parameters.Enlarge
Program Post-Synthesis Modification
Versatile options enabling orthogonal deprotection for modifications like branching and cyclization.Enlarge
Full Suite of Calculator Tools
Convenient calculators provide the reagents and amounts for a run.Enlarge
Pause, Edit, Monitor at any Step
Easily pause, edit, and monitor reactions from the run screen.Enlarge
Applications
Synthesize standard and complex peptides.
The Liberty 2.0 series, like preceding models, utilizes CEM’s High-Efficiency Solid Phase Peptide Synthesis (HE-SPPS) and CarboMAX coupling methodologies.View Application Data
Cyclized Peptides
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Disulfide Bonding
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Glycopeptides (N/O-linked)
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N-Methyl Peptides
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Peptoids
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Accessories and Related Products
HT4
The HT4 automates peptide synthesis with the ability to queue up to 4 peptides. New reactions can be programmed at any time, even while another sample is running.Learn More
HT12
The HT12 option for the Liberty Blue and Liberty Prime provides automation for up to 12 peptides. New peptides can be added and programmed at any time, even while another sample is running.Learn More
Razor
The Razor from CEM provides high temperature, rapid cleavage on up to 12 samples simultaneously. Finish cleavage in just 30 minutes with the Razor.Learn More
Prodigy
The Prodigy Preparative HPLC is a purification system optimized for use with biomolecules like peptides and proteins. The fully integrated temperature control for the column and mobile phase is a powerful tool, especially for difficult or hydrophobic samplesLearn More