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Automated N-Terminal Acetylation

October 12, 2018
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The Liberty Blue can accomodate a wide range of post-synthetic modifications such as N-terminal acetylation.  Microwave-enhanced SPPS on the Liberty Blue produced nonacetylated and acetylated peptides at 78% and 72% respecitivly with a combined time of 2 hr 16 min and a total of < 200 mL of main wash (DMF) consumed.