Microwave Peptide Synthesizer
Liberty Lite 2.0

A powerful peptide synthesizer.

 

Overview


The Liberty Lite™ 2.0 provides advantages over existing peptide synthesizers with its patented use of microwave irradiation during both the deprotection and coupling steps (12 minute cycle times), in-situ temperature control, Flex-Add™ delivery system, and efficient solvent usage.



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Unique Chemistry

  • Microwave deprotection and coupling (patented)
  • CarboMAX™ coupling chemistry (patented)

Features

  • 12 min Cycle Time
  • Flex-Add™ critical reagent delivery system (patented)
  • True Internal fiber-optic temperature control
  • 0.005 - 5 mmol scale range
  • 27 amino acid positions

CarboMAX

CarboMAX

The best coupling method for peptide synthesis.

  • The fastest and most complete coupling
  • Stabilizes acid sensitive linkages which are problematic for standard carbodiimide chemistry (phospho, glyco, hyper-acid linkages)
  • Unmatched low-level of epimerization for all 20 amino acids due to faster activation (faster o-acylisourea formation)

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CarboMAX

FlexAdd

The best way to deliver critical reagents.

  • Infinitley variable- unlike sample loops, Flex-Add™ can deliver any desire volume
  • No reagents lost to priming ever
  • Optimized for waste reduction


High Throughput (HT) Loaders

High Throughput (HT) Loaders

High-throughput peptide synthesis made easy.

  • Add additional peptides at any time, even while the instrument is running with an HT accessory
  • No input required once the synthesis is started
  • Individual 20mer's completed every 4 hours

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Software

Flexible, Powerful Software

The newly updated software is both flexible and easy to use, making sure nothing stands between you and your synthesis. Customize methods with unique monomers, orthogonal deprotection, branching, cyclizing, and more. Easily check on reactions on the run screen, where the run can be edited, paused, and resumed at any time.



Method Editor

Easy and Flexible Sequence Programming

The method editor on the Liberty Lite 2.0 allows full customization of reaction parameters.

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Alternate Chemistry and Post-Synthetic Modification

Program Post-Synthesis Modification

Versatile options enabling orthogonal deprotection for modifications like branching and cyclization.

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Calculator for Reagents

Full Suite of Calculator Tools

Convenient calculators provide the reagents and amounts for a run.

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Edit on the Run

Pause, Edit, Monitor at any Step

Easily pause, edit, and monitor reactions from the run screen.

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Applications

Synthesize standard and complex peptides.

The Liberty 2.0 series, like preceding models, utilizes CEM’s High-Efficiency Solid Phase Peptide Synthesis (HE-SPPS) and CarboMAX coupling methodologies.

Branched Peptides
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Cyclized Peptides
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Disulfide Bonding
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Glycopeptides (N/O-linked)
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High Throughput Synthesis
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N-Methyl Peptides
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Peptoids
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Phosphopeptides
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Accessories and Related Products



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