Welcome to CEM.com

Liberty PRIME Proves Successful in New Research

May 17, 2018

Liberty PRIME Seminar at Osaka, Japan


New peptide synthesis research using the Liberty PRIME peptide synthesizer was presented on Aprill 22nd and 24th in a series of seminars in Tokyo and Osaka, Japan.  The research showed the highly efficient synthesis of a wide range of peptides including cyclotides, N-methyl peptides, and glucagon-like peptides. The unique methodology and instrument design of the Liberty PRIME allows for major synthesis improvements over CEM's best selling Liberty Blue line of peptide synthesizers.


Liberty Blue Synthesis of ABC 20mer


Figure 1:  UPLC Chromatogram of ABC 20mer Synthesized on the Liberty Blue

Liberty PRIME Synthesis of ABC 20mer


Figure 2:  UPLC Chromatogram of ABC 20mer Synthesized on the Liberty PRIME


 

 Table 1:  Synthesis of VYWTSPFMKLIHEQCNRADG-NH(ABC 20mer) on the Liberty Blue and Liberty PRIME 

InstrumentCrude PuritySynthesis TimeWash (DMF) RequirementTotal Waste
Liberty Blue 77% 93 min 187 mL 340 mL
Liberty PRIME 83% 46 min 88 mL 168 mL