Microwave Peptide Synthesizer
Liberty 2.0
A powerful entry-level peptide synthesizer.
Overview
The entry-level system for CEM’s best in class microwave peptide synthesizer line. The Liberty 2.0 provides advantages over existing peptide synthesizers with it’s patented use of microwave irradiation during both the deprotection and coupling steps (12 minute cycle times), in-situ temperature control, Flex-Add™ delivery system, and efficient solvent usage.
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Unique Chemistry
- Microwave deprotection and coupling (patented)
- CarboMAX™ coupling chemistry (patented)
Features
- 12 min Cycle Time
- Flex-Add™ critical reagent delivery system (patented)
- True Internal fiber-optic temperature control
- 0.005 - 5 mmol scale range
- 27 amino acid positions
CarboMAX
The best coupling method for peptide synthesis.
- The fastest and most complete coupling
- Stabilizes acid sensitive linkages which are problematic for standard carbodiimide chemistry (phospho, glyco, hyper-acid linkages)
- Unmatched low-level of epimerization for all 20 amino acids due to faster activation (faster o-acylisourea formation)
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High Throughput (HT) Loaders
High-throughput peptide synthesis made easy.
- Automated synthesis of 4 peptides (individual 20mer’s completed every 4 hours)
- The Liberty 2.0 paired with the HT4 allows for automated synthesis of 4 peptides
- Individual 20mer's completed every 4 hours
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Software
Flexible, Powerful Software
The newly updated software is both flexible and easy to use, making sure nothing stands between you and your synthesis. Customize methods with unique monomers, orthogonal deprotection, branching, cyclizing, and more. Easily check on reactions on the run screen, where the run can be edited, paused, and resumed at any time.
Easy and Flexible Sequence Programming
The method editor on the Liberty Blue allows full customization of reaction parameters.Enlarge
Program Post-Synthesis Modification
Versatile options enabling orthogonal deprotection for modifications like branching and cyclization.Enlarge
Full Suite of Calculator Tools
Convenient calculators provide the reagents and amounts for a run.Enlarge
Pause, Edit, Monitor at any Step
Easily pause, edit, and monitor reactions from the run screen.Enlarge
Applications
Synthesize standard and complex peptides.
The Liberty 2.0 series, like preceding models, utilizes CEM’s High-Efficiency Solid Phase Peptide Synthesis (HE-SPPS) and CarboMAX coupling methodologies.View Application Data
Cyclized Peptides
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Disulfide Bonding
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Glycopeptides (N/O-linked)
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N-Methyl Peptides
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Peptoids
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Accessories and Related Products
HT4
The HT4 automates peptide synthesis with the ability to queue up to 4 peptides. New reactions can be programmed at any time, even while another sample is running.Learn More
Razor
The Razor from CEM provides high temperature, rapid cleavage on up to 12 samples simultaneously. Finish cleavage in just 30 minutes with the Razor.Learn More
Prodigy
The Prodigy Preperative HPLC is a purification system optimized for use with biomolecules like peptides and proteins. The fully integrated temperature control for the column and mobile phase is a powerful tool, especially for difficult or hydrophobic samplesLearn More