Polystyrene Resins

Wang resins at an economical price.

Polystyrene Resins

Overview
The 4-alkoxy-substituted benzyl moiety (Wang) linker is commonly used for Fmoc chemistry. This linker is stable to basic conditions, but cleaved smoothly under acidic conditions with ≥ 90% trifluoroacetic acid (TFA) to furnish a peptide acid. Coupling of the first amino acid to the linker is typically done with 4-(Dimethylamino)pyridine (Dmap) as a catalyst. This step is subject to unwanted side reactions and can be problematic. For convenience, Wang resins are typically supplied pre-loaded with the first amino acid.
Standard Specifications
  • Loading range: 0.15 – 0.80 mmol/g
  • Mesh size: 100 – 200 mesh

Pre-Loaded PS Resin

Convenient synthesis of peptide acids.

Modern SPPS is most effectively utilized with instrumentation to automate and accelerate the reaction process. The resin can be loaded into the instrument along with a bank of amino acids in solution and reactions can run autonomously. Microwave heating can be used to dramatically increase the rate and purity of the reaction.

Color Key
 

Resin
 

Wang Linker
 

Generic Amino Acid
 

Base-Labile Fmoc Protecting Group

Products

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  • Fmoc-Ala-Wang Resin (LL)

    #R100-C100 g
    $1,145
    #R100-B525 g
    $375
    #R100-B5 g
    $78

  • Fmoc-Arg(Pbf)-Wang Resin (LL)

    #R101-C100 g
    $1,455
    #R101-B525 g
    $410
    #R101-B5 g
    $88

  • Fmoc-Asn(Trt)-Wang Resin (LL)

    #R102-C100 g
    $1,405
    #R102-B525 g
    $410
    #R102-B5 g
    $88

  • Fmoc-Asp(OtBu)-Wang Resin (LL)

    #R103-C100 g
    $1,405
    #R103-B525 g
    $410
    #R103-B5 g
    $88

  • Fmoc-Gln(Trt)-Wang Resin (LL)

    #R104-C100 g
    $1,405
    #R104-B525 g
    $410
    #R104-B5 g
    $88

  • Fmoc-Glu(OtBu)-Wang Resin (LL)

    #R105-C100 g
    $1,405
    #R105-B525 g
    $410
    #R105-B5 g
    $88

  • Fmoc-Glu(Wang)-ODmab Resin (LL)

    #R120-A1 g
    $92
    #R120-B5 g
    $425

  • Fmoc-Glu(Wang)-OAll PS Resin (LL)

    #R121-B5 g
    $470
    #R121-A1 g
    $88

  • Fmoc-Gly-Wang Resin (LL)

    #R106-C100 g
    $1,145
    #R106-B525 g
    $375
    #R106-B5 g
    $78

  • Fmoc-His(Boc)-Wang Resin (LL)

    #R119-C100 g
    $1,405
    #R119-B525 g
    $410
    #R119-B5 g
    $88

  • Fmoc-Ile-Wang Resin (LL)

    #R108-C100 g
    $1,145
    #R108-B525 g
    $375
    #R108-B5 g
    $78

  • Fmoc-Leu Wang Resin (LL)

    #R109-C100 g
    $1,145
    #R109-B525 g
    $375
    #R109-B5 g
    $83

  • Fmoc-Lys(Boc)-Wang Resin (LL)

    #R110-C100 g
    $1,405
    #R110-B525 g
    $410
    #R110-B5 g
    $88

  • Fmoc-Met-Wang Resin (LL)

    #R111-C100 g
    $1,080
    #R111-B525 g
    $310
    #R111-B5 g
    $64

  • Fmoc-Phe-Wang Resin (LL)

    #R112-C100 g
    $1,145
    #R112-B525 g
    $375
    #R112-B5 g
    $78

  • Fmoc-Pro-Wang Resin (LL)

    #R118-C100 g
    $1,145
    #R118-B525 g
    $375
    #R118-B5 g
    $78

  • Fmoc-Ser(tBu)-Wang Resin (LL)

    #R113-C100 g
    $1,405
    #R113-B525 g
    $410
    #R113-B5 g
    $88

  • Fmoc-Thr(tBu) Wang Resin (LL)

    #R114-C100 g
    $1,405
    #R114-B525 g
    $410
    #R114-B5 g
    $88

  • Fmoc-Trp(Boc)-Wang Resin (LL)

    #R115-C100 g
    $1,405
    #R115-B525 g
    $410
    #R115-B5 g
    $88

  • Fmoc-Tyr(tBu) Wang Resin (LL)

    #R116-C100 g
    $1,405
    #R116-B525 g
    $410
    #R116-B5 g
    $88

  • Fmoc-Val Wang Resin (LL)

    #R117-C100 g
    $1,145
    #R117-B525 g
    $375
    #R117-B5 g
    $78